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Probiotics have beneficial metabolic effects in patients with type 2 diabetes mellitus: a meta‑analysis of randomized clinical trials

Admin Clinical Papers July 16, 2020

Probiotics have been reported to have a positive impact on the metabolic control of patients with type 2 diabetes. We aimed to systematically evaluate the effects of probiotics on cardiometabolic parameters in type 2 diabetes based on randomized controlled studies. MEDLINE, Embase, and CENTRAL databases were reviewed to search for…

Gut microbiota and metabolic syndrome

Admin Clinical Papers April 5, 2020

Metabolic syndrome (MetS) describes a set of risk factors that can eventually lead to the occurrence of cardiovascular andcerebrovascular disease. A detailed understanding of the MetS mechanism will be helpful in developing effective preventionstrategies and appropriate intervention tools.

Probiotics in late infancy reduce the incidence of eczema: A randomized controlled trial

Admin Clinical Papers December 13, 2018

Background: Allergic diseases are common and represent a considerable health and economic burden worldwide. We aimed to examine the effect of a combination of two probiotic strains administered in late infancy and early childhood on the development of allergic diseases and sensitization. Methods: In this double‐blind, placebo‐controlled intervention trial, participants…

Systematic review with meta‐analysis: the efficacy of prebiotics, probiotics, synbiotics and antibiotics in irritable bowel syndrome

Admin Clinical Papers October 8, 2018

Particular combinations of probiotics, or specific species and strains, appeared to have beneficial effects on global IBS symptoms and abdominal pain, but it was not possible to draw definitive conclusions about their efficacy. There were five trials of similar design that used rifaximin in non-constipated IBS patients, which was more…

Effect of LC9018 combined with radiation therapy on carcinoma of the uterine cervix. A phase III, multicenter, randomized, controlled study

Admin Clinical Papers September 15, 1993

Background. The failure rate with radiation therapy alone for Stage III cervical cancer is quite high, and therefore other modalities are being pursued as adjuvants to radiation therapy in hopes of improving the results. Methods. A randomized, controlled, comparative study on the efficacy and safety of radiation therapy combined with…