Posts Tagged

permeability

Brain-gut-microbiota axis in Alzheimer’s disease

Admin Clinical Papers January 1, 2019

Alterations in the gut microbiota composition induce increased permeability of the gut barrier and immune activation leading to systemic inflammation, which in turn may impair the blood-brain barrier and promote neuroinflammation, neural injury, and ultimately neurodegeneration. The Aβ seeding and propagation may occur at different levels of the brain-gut-microbiota axis.…