Posts Tagged

neurodegenerative

Brain-gut-microbiota axis in Alzheimer’s disease

Admin Clinical Papers January 1, 2019

Alterations in the gut microbiota composition induce increased permeability of the gut barrier and immune activation leading to systemic inflammation, which in turn may impair the blood-brain barrier and promote neuroinflammation, neural injury, and ultimately neurodegeneration. The Aβ seeding and propagation may occur at different levels of the brain-gut-microbiota axis.…

Colonic Bacterial Composition in Parkinson’s Disease

Admin Clinical Papers July 16, 2015

Sixty-six sigmoid mucosal biopsies and 65 fecal samples were collected from 38 PD patients and 34 healthy controls. The mucosal and fecal microbial community of PD patients was significantly different than control subjects, with the fecal samples showing more marked differences than the sigmoid mucosa. At the taxonomic level of…