Posts Tagged


Gut microbiota and metabolic syndrome

Admin Clinical Papers April 5, 2020

Metabolic syndrome (MetS) describes a set of risk factors that can eventually lead to the occurrence of cardiovascular andcerebrovascular disease. A detailed understanding of the MetS mechanism will be helpful in developing effective preventionstrategies and appropriate intervention tools.

Brain-gut-microbiota axis in Alzheimer’s disease

Admin Clinical Papers January 1, 2019

Alterations in the gut microbiota composition induce increased permeability of the gut barrier and immune activation leading to systemic inflammation, which in turn may impair the blood-brain barrier and promote neuroinflammation, neural injury, and ultimately neurodegeneration. The Aβ seeding and propagation may occur at different levels of the brain-gut-microbiota axis.…

Colonic Bacterial Composition in Parkinson’s Disease

Admin Clinical Papers July 16, 2015

Sixty-six sigmoid mucosal biopsies and 65 fecal samples were collected from 38 PD patients and 34 healthy controls. The mucosal and fecal microbial community of PD patients was significantly different than control subjects, with the fecal samples showing more marked differences than the sigmoid mucosa. At the taxonomic level of…

Microbial influences in inflammatory bowel diseases

Admin Clinical Papers February 1, 2008

Clinical, experimental, and therapeutic studies suggest an important role for microbial agents in Crohn’s disease and pouchitis pathogenesis. Bar-nich and Darfeuille-Michaud described adherent/invasive E. coli (AIEC) that persist within epithelial cells and macrophages and selectively colonize the ileum of Crohn’s disease patients.