Posts Tagged


Systematic review with meta‐analysis: the efficacy of prebiotics, probiotics, synbiotics and antibiotics in irritable bowel syndrome

Admin Clinical Papers October 8, 2018

Particular combinations of probiotics, or specific species and strains, appeared to have beneficial effects on global IBS symptoms and abdominal pain, but it was not possible to draw definitive conclusions about their efficacy. There were five trials of similar design that used rifaximin in non-constipated IBS patients, which was more…

Identification of an Intestinal Microbiota Signature Associated With Severity of Irritable Bowel Syndrome

Admin Clinical Papers January 1, 2017

Fecal microbiota showed covariation with mucosal adherent microbiota.We confirmed the robustness of the intestinal microbial signature for severe IBS in the validation set. The signature was able to discriminate between patients with severe symptoms, patients with mild/moderate symptoms, and healthy subjects. By using this intestinal microbiota signature, we found IBS…

The gut microbiome in health and in disease

Admin Clinical Papers January 1, 2016

There is a fast growing collection of data describing the structure and functional capacity of themicrobiome in a variety of conditions available to the research community for consideration and furtherexploration. Ongoing efforts to further characterize the functions of the microbiome and the mechanismsunderlying host–microbe interactions will provide a better understanding…

Molecular analysis of the luminal- and mucosal-associated intestinal microbiota in diarrhea-predominant irritable bowel syndrome

Admin Clinical Papers July 7, 2011

Molecular fingerprinting of the microbiota from fecal and colonic mucosal samples revealed differences in the contribution of T-RFs to the microbiota between D-IBS patients and healthy controls. Further analysis revealed a significantly lower (1.2-fold) biodiversity of microbes within fecal samples from D-IBS patients than healthy controls (P 0.008). No difference…