Posts Tagged

GI symptoms

Persistent gut microbial dysbiosis in children with Acute Lymphoblastic Leukemia (ALL) during chemotherapy

Admin Clinical Papers November 21, 2019

We observe that the microbiota diversity and richness of the ALL group is significantly lower than that of the control group at diagnosis and during chemotherapy. The microbiota diversity is even lower in antibiotics-exposed ALL patients. Although the gut microbial diversity tends to stabilize after 1-year post-chemotherapy, their abundances were…

Long-term benefit of microbiota transfer therapy on autism symptoms and gut microbiota

Admin Clinical Papers April 9, 2019

Many studies have reported abnormal gut microbiota in individuals with Autism Spectrum Disorders (ASD), suggesting a link between gut microbiome and autism-like behaviors. Modifying the gut microbiome is a potential route to improve gastrointestinal (GI) and behavioral symptoms in children with ASD, and fecal microbiota transplant could transform the dysbiotic…

Review article: the gut microbiome in inflammatory bowel disease—avenues for microbial management

Admin Clinical Papers May 29, 2017

Disease remission and relapse are associated with microbial changes in both mucosal and luminal samples. In particular, a loss of species richness in Crohn’s disease has been widely observed. Existing therapeutic approaches broadly fall into 3 categories, namely: accession, reduction or indirect modulation of the microbiome. In terms of microbial…

Identification of an Intestinal Microbiota Signature Associated With Severity of Irritable Bowel Syndrome

Admin Clinical Papers January 1, 2017

Fecal microbiota showed covariation with mucosal adherent microbiota.We confirmed the robustness of the intestinal microbial signature for severe IBS in the validation set. The signature was able to discriminate between patients with severe symptoms, patients with mild/moderate symptoms, and healthy subjects. By using this intestinal microbiota signature, we found IBS…