Gut Check


Information to Insights

“Simplicity is the ultimate sophistication” – Leonardo Da Vinci What happens after our lab receives your sample? And how does your sample translate into a colourful report with straightforward findings and easy to follow recommendations?  This is what happens in the AMILI lab. Your stool sample is assessed physically, processed, and then the genetic material …

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A randomized controlled trial of the efficacy of systemic enzymes and probiotics in the resolution of post-COVID fatigue

Muscle fatigue and cognitive disturbances persist in patients after recovery from acuteCOVID-19 disease. However, there are no specific treatments for post-COVID fatigue. Objective: Toevaluate the efficacy and safety of the health supplements ImmunoSEB (systemic enzyme complex)and ProbioSEB CSC3 (probiotic complex) in patients suffering from COVID-19 induced fatigue.A randomized, multicentric, double blind, placebo-controlled trial was conducted in 200 patientswith a complaint of post-COVID fatigue. The test arm (n= 100) received the oral supplements for14 days and the control arm (n= 100) received a placebo. Treatment efficacy was compared usingthe Chalder Fatigue scale (CFQ-11), at various time points from days 1 to 14. The supplementaltreatment resulted in resolution of fatigue in a greater percentage of subjects in the test vs. the controlarm (91% vs. 15%) on day 14. Subjects in the test arm showed a significantly greater reductionin total as well as physical and mental fatigue scores at all time points vs. the control arm. Thesupplements were well tolerated with no adverse events reported. This study demonstrates that a14 days supplementation of ImmunoSEB + ProbioSEB CSC3 resolves post-COVID-19 fatigue and canimprove patients’ functional status and quality of life.

Diet, microbiome, and cancer immunotherapy—A comprehensive review

This review shows that specific dietary patterns (such as, e.g., animal-based, vegetarian, or Mediterranean diet) alter the gut microbiome’s composition. An appropriate intestinal microbiota structure might modulate the function of human immune system, which affects the bodily anti-cancer response. This paper shows also that specific bacteria species inhabiting the gastrointestinal tract can have a beneficial influence on the efficacy of immunotherapy. Antibiotics weaken gut bacteria and worsen the immune checkpoint blockers’ efficacy, whereas a faecal microbiota transplant or probiotics supplementation may help restore bacterial balance in the intestine. Other factors (like vitamins, glucose, or BMI) change the cancer treatment response, as well. This review demonstrates that there is a strong association between one’s diet, gut microbiome composition, and the outcome of immunotherapy. However, further investigation on this subject is required.

Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation

Our results indicate that overweight or obesity is a favorable prognostic factor independent of gut diversity. In addition, our results demonstrate that patients with better clinical survival exhibit higher diversity as well as a distinct gut microbiome composition. At last, the association between gut diversity and local immune signatures suggests that patients with high gut diversity develop increased infiltration of activated CD4+ T-cell subsets and highlights helper CD4+ T cells as potential mediators of antitumor immunity upon CRT treatment.

Diabetes and the Gut Microbiome

Share on facebook Facebook Share on google Google+ Share on twitter Twitter Share on linkedin LinkedIn One of the ways your diet affects your health status is by modulating the composition of your gut microbiota. It has been found that normal gut microbiota affects the development of the immune system, nutrient absorption, tissue generation and …

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Bacteroidetes and Firmicutes: What’s the Deal?

Share on facebook Facebook Share on google Google+ Share on twitter Twitter Share on linkedin LinkedIn The gut microbiome is the collection of bacteria, archaea, and eukarya that reside in the human gastrointestinal tract. Due to its roles in a broad range of physiological functions, the gut microbiome is now thought of as an organ …

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Let Us Get to Know Lactobacillus

Share on facebook Facebook Share on google Google+ Share on twitter Twitter Share on linkedin LinkedIn Just like you and me, bacteria have families too. One such family is the Lactobacillaceae, a group of bacteria characterized by their lactic acid-producing capabilities. Family members generally share the same characteristics. For example, Lactobacilliceae have the ability to …

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How Does the Chinese New Year Diet Change our Gut Microbiome?

Share on facebook Facebook Share on google Google+ Share on twitter Twitter Share on linkedin LinkedIn Chinese New Year is a festival celebrated by many worldwide. Various traditions like having reunion dinner with your extended family, consuming various festive treats, and beautifying your house with a variety of streamers and banners are all common during …

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