Gut Microbiota in Patients With Irritable Bowel Syndrome—A Systematic Review

January 7, 2019

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Altering the gut microbiota has been proposed as a strategy for the treatment of IBS, but the association between the gut microbiome and IBS symptoms has not been well established. Most studies evaluated adults presenting with various IBS subtypes. Family Enterobacteriaceae (phylum Proteobacteria), family Lactobacillaceae, and genus Bacteroides were increased in patients with IBS compared with controls, whereas uncultured Clostridiales I, genus Faecalibacterium (including Faecalibacterium prausnitzii), and genus Bifidobacterium were decreased in patients with IBS. The diversity of the microbiota was either decreased or not different in IBS patients compared with controls.