Clinical Papers

Food: The main course to wellness and illness in patients with irritable syndrome

September 2, 2016

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Food sits at the intersection between gastrointestinal (GI) physiology and symptoms in patients with irritable bowel syndrome (IBS). It is now clear that the majority of IBS sufferers associate eating a meal with their GI and non-GI symptoms. Investigators from Sweden found that over 80% of their symptoms were with their food. There is mounting evidence that food exerts effects on motility, visceral sensation, brain-gut interactions, microbiome, permeability, immune activation, and neuro-endocrine function—all key factors that have been implicated in the pathogenesis of GI symptoms.