Food: The main course to wellness and illness in patients with irritable syndrome

Food sits at the intersection between gastrointestinal (GI) physiology and symptoms in patients with irritable bowel syndrome (IBS). It is now clear that the majority of IBS sufferers associate eating a meal with their GI and non-GI symptoms. Investigators from Sweden found that over 80% of their symptoms were with their food. There is mounting evidence that food exerts effects on motility, visceral sensation, brain-gut interactions, microbiome, permeability, immune activation, and neuro-endocrine function—all key factors that have been implicated in the pathogenesis of GI symptoms